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ABSTRACT
The article presents the challenges of sequencing in Operation Research and propose a comprehensive methodology to address these issues. The methodology includes problem formulation, data collection, mathematical modelling, solution techniques, algorithm implementation, performance evaluation, experimental validation, sensitive analysis and comparative assessment. This systematic approach provides a rigorous framework for tackling a wide range of sequencing challenges. The methodology is versatile and can be use by researchers and practitioners across industries to optimize processes and make informed decisions.