THE PROTECTIVE EFFECTS OF THE ETHANOLIC LEAF EXTRACT OF CENTELLA ASIATICA ON MERCURIC CHLORIDE INDUCED CEREBELLAR DAMAGE ON ADULT Wistar RATS

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ABSTRACT

According to the study's findings, mercuric chloride significantly damaged the cerebellum, resulting in the depletion of the purkinje cell layer. Additionally, the ethanolic leaf extract of Centella 54 asiatica did not significantly improve the oxidative stress parameters. According to the results, there was a protective effect against the cerebellar cortical damage caused by mercuric chloride from a histological perspective. This is consistent with a book published in 2019 by Chiroma et al., which suggests that Centella asciatica may provide protection against morphological changes and cognitive decline.

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