THE EFFECTS OF DAILY INTAKE OF AQUEOUS FRUIT PULP EXTRACT OF PICRALIMA NITIDA

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ABSTRACT

There is a growing need for the utilization of medicinal plant to control hyperglycaemia. This study was designed to assess the daily administration of unripe Picralima nitida aqueous fruit pulp extract on experimental rats. 30 rats were divided into five groups with each group containing 5 rats each. Group A was the control group and they were fed with the rat feed and water throughout the projects duration. Group B - F received 200mg, 500mg, 1000mg, 2000mg and 3000mg of the plant extract dissolved in distilled water using a galvage respectively. Blood glucose levels were assessed every 3 days for 35 days using a glucometer. The results revealed that the unripe P. nitida aqueous fruit pulp extract possess the ability to reduce blood glucose. The 2000mg extract was the effective dose, causing a reduction of 41.38% in experimental rats. Therefore, the unripe P. nitida aqueous fruit pulp extract could be used as an adjuvant to control blood glucose level.

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