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This study examined the relationship between tax revenue and economic growth in Nigeria from 1994 to 2022 (28 years).The objectives were to determine the effect Petroleum Profit Tax on economic growth in Nigeria, to assess the impact of Company Income Tax on economic growth in Nigeria, to analyse the significance of Value Added Tax on economic growth in Nigeria, and to examine the relationship between Custom and Excise duty and economic growth in Nigeria. Time series data were gotten and analysed using the Ordinary Least Squares (OLS) econometric technique to examine the relationship between the variables. The study found that custom and excise duties have a negative significant impact on real gross domestic product in Nigeria, that company income tax has no significant impact on real gross domestic product in Nigeria, that petroleum profit tax has no significant impact on real gross domestic product in Nigeria, and thatvalue added tax has a positive significant impact on real gross domestic product in Nigeria. It was concluded that the Nigerian government should ensure sustainable tax revenue mobilization policies so as to leverage on real gross domestic product and development both in the short term and long term. The study also recommends that the government should strengthen and streamline the tax system to ensure adequate mobilization of tax revenue, reduce inefficiencies, and widen the tax base for economic growth