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ABSTRACT
The synthesis of Silver nanoparticles (AgNPs) by Curcuma longa rhizomes extract is reported in this study, demonstrating the potential of nanotechnology in biochemical research. This study reports the synthesis, characterization and medicinal properties of silver nanoparticles (AgNPs) from Curcuma longa rhizomes extract. Crude aqueous and ethanol extracts of Curcuma longa rhizomes were used to synthesize AgNPs, which were then characterized using UV-Vis spectroscopy, Fourier-transform infrared spectroscopy (FTIR), Scanning Electron Microscopy(SEM) and X-ray diffraction (XRD) and determination of their medicinal properties. The anti-microbial efficacy of AgNPs against methicillin-resistant staphylococcus aureus (MRSA) and their antioxidant protections, showed the effectiveness of the nanoparticle-plant extract complex in scavenging free radicals compared to ascorbic acid indicating their potential for therapeutic applications. The UV-Vis spectra of AgNPs showed maximum absorbance at 450nm and 500nm for F1 and F2, respectively, indicating the formation of AgNPs. The FTIR spectra revealed the presence of functional groups corresponding to the plant extract and AgNPs. XRD analysis confirmed the crystalline structure of AgNPs, with 11 peaks indexed to different planes. SEM images showed a diverse range of small clusters of spherical, cubic, and pebble-like particles. The results suggest that C. longa rhizomes extract can be used to synthesize AgNPs with potential medicinal properties. The AgNPs exhibited antioxidant and antimicrobial activities, indicating their potential use in treating various diseases. Further studies are needed to fully explore the medicinal properties of AgNPs synthesized by C. longa.
