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ABSTRACT
Medicinal plants generally contain substances that have therapeutic functions; however, they are potentially toxic. This current study investigate the toxicity of aqueous and methanol extracts of Acalypha wilkisiana leaves on both the organs of albino rats. Acalypha wikesiana is one of those ethno medicinal plants with health benefits. It is found worldwide mostly around the tropical of Africa, America and Asia. Its leaves juice is drunk with water to treat diarrhoea and dysentery. Boiled leaves are used to massage people suffering from fever. An infusion of leaves and bark is drunk as a treatment for pleurisy. The leaves are squeezed and mixed with water, and drunk to regulate menstruation. A decoction of the leaves is used to treat gastritis and lymphoid swellings. Fresh leafy branches are externally applied to induce perspiration, apparently for their rubefacient effect. Similarly, heated leaves are applied to cure fevers. Likewise fresh or heated leaves are externally applied to relieve rheumatic pains, inflammations and swellings. The water extract of the reddish form is traditionally used for treating skin problems. This project work provides relatively concise information gathered from studies carried out in the laboratory and data published by other scientists who have worked on the plant. The project focuses on the therapeutic and toxic profile of Acalypha wilkesiana. The current study investigate the toxicity of aqueous and methanol extracts of Acalypha wilkisiana leaves on both the organs and blood of albino rats.
