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This paper examines product mix optimization in the manufacturing industry using linear programming approach. Guinness Nigeria Plc, Benin was understudied. The company was chosen because it deals on different products which make the determination of the quantity combinations of the products produced and sold an important and major management decision. Thirteen products of the company (Dubic Malt, Guinness Stout (Medium), Harp, Herbal Malt, Malta Guinness, Orijin Herbs, Orijin Bitters, Orijin Zero, Satzenbrau, Smirnoff Double Black, Smirnoff Ice, Snap and Tappers) were sampled for the study. Data were sourced from the records of the company. Linear programming of the operations of the company was formulated and optimum results derived using Linear Programming Software (Lips) that employed simplex method. Based on the data collected and analyzed, it was discovered that, given the amount of materials available, the company should produce all the products in order to satisfy its customers but more of Satzenbrau should be produced in order to attain maximum profit because they contribute most to the profit earned. It is therefore recommended that any product having an adverse effect or contributing losses to the profit margin of the company can be stopped and the company can focus on those that can generate more profit.