COMPARISION OF THE ETHANOL AND AQUEOUS EXTRACT OF Salvia hispanica (CHIA SEEDS) ON ANTI-PANCREATIC LIPASE ACTIVITY

ABSTRACT

Salvia species have been traditionally used in the treatment of colds, aches and pains, infections, wounds, bronchitis, flu, tuberculosis, haemorrhage, insomnia, some cardiovascular and menstrual disorders, stomach, liver, and rheumatism pain. This is due to their bioactive constituents such as terpenoids, phenolics, essential oils, and fatty acids) that give them their medicinal properties. The aim of the study was to evaluate the anti-obesity of Salvia hispanica seeds (chia seeds) by investigating the anti-pancreatic lipase activity of the seed. The objective of the study was to determine the anti-pancreatic lipase activity of Salvia hispanica. The standard anti-obesity drug (Orlistat) was used as a control. The data obtained was analysed using a Graphpad prisim version 8.0.3.The results showed that the ethanol extract had a greater anti-pancreatic lipase activity (IC₅₀:870.47µg/ml) when compared to the aqueous extract (IC₅₀: 2866.58µg/ml) and the standard (Orlistat) (IC₅₀:2338µg/ml) making it a viable management option for obesity and related metabolic syndrome.