ABSTRACT
Antimicrobial resistance (AMR) of different bacterial strain shows resistance against antibiotics that normally inhibit or stop their growth and allow them to withstand against drugs.The present study was designed to assess the prevalence of MDRE among outpatients presenting to two primary health centre (Evbougida and Evboutubu) in Egor LGA Benin city, Nigeria; a cross-sectional study using standard culture-based methods. A total of 48 urine and swab samples were studied between March 2021 to May 2021. Microbial enumeration and identification were carried out using cultural and biochemical methods. Microbial counts were carried out using cultural characterization, Gram staining techniques and biochemical tests including; oxidase, indole, sugar fermentation, nitrate reduction test, citrate, motility, methyl red, catalase, urease and antimicrobial susceptibility test (using Kirby-Bauer disc diffusion technique) using oral antibiotics such as Gentamycin, Ofloxacin, Augmentin, Ampicillin, Amikacin, Ciprofloxacin, Nitrofurantoin, Ceftazidime, and Cefuroxime. Most of the samples tested were positive for E.coli with the highest occurring in females at 75.9%and the distribution of MDRE (93.7%) was determined from the study samples with 84.4% of females showing more resistance to antimicrobials used in the study between the ages of 25-34 with occupations including hair dressing, tailoring etc., and an income of 11,000-99,999 as their socio-demographic characteristics were observed in the month of march and may respectively. Findings from this study revealed MDRE had high prevalence in the distribution by participants social demographic characteristics. Hence, MDRE poses a potential public health risk and therefore, MDR awareness and hygienic precautions should be taken.
