ANTIFERTILITY ACTIVITY OF N-HEXANE EXTRACT OF BI-HERBAL FORMULATION OF Carica papaya AND Veronica amygdalina LEAVES (VERCARIM) ON LABORATORY MICE

ABSTRACT

Over population has become a problem worldwide thus the need for drugs with side effects compared to known orthodox drugs. At present there are reports that pregnant women who used the bi-herbal formulation during early pregnancy noticed that it caused abortion, thus the need scientifically investigate the bi-herbal formulation of carica papaya leaf and vernonia amygdalin pregnant and non pregnant albino wistar rats. The n-hexane estract of bi-herbal formulation of carica papaya leaf and vernonia amygdalin was administered to female animals orally at the doses of 30, 60 and 120 mg/kg per day for 14 days by mating and after confirmation of pregnancy respectively.